Scorpion venom disrupts the nervous system in various ways and at various levels. Understanding the severity of symptoms is vital for appreciating the urgency of the situation, pre-empting any future symptoms, and challenges that may occur while transporting the patient to medical assistance.
The following classes of symptoms are the foundations for effective first response.

In southern Africa, the vast majority of scorpion stings result in little more than class 1 and 2 symptoms, requiring no professional medical intervention whatsoever. At the other extreme, southern Africa is home to 3 species of scorpion that are collectively responsible for an estimated 8 to 12 deaths per year.
These classes also relate to bites and stings from other venomous animals, such as spiders, snakes, stingrays, stone fish, centipedes, bees and wasps. These classes do not increase in equal steps nor on a linear scale, but rather infer symptoms, define boundaries, and indicate response. These classes relate to the sum of the patient’s symptoms.
Scorpion sting symptoms can be divided into localised and systemic symptoms. Recognising and understanding how symptoms develop is important for effective first response.
Understanding how symptoms develop and the associated time frames, offer insight into the progression of symptoms from localised to systemic (if any).
The risk of bacterial infection is low because the sting site does not develop into an open lesion. The antibacterial properties of scorpion venom may also reduce the risk of bacterial infection. the use of antihistamines is not advised unless the patient is experiencing an allergic reaction. Life threatening allergic reactions to scorpion venom are very rare.
The majority of scorpion stings in humans occur when picking up objects under or in which a scorpion is sheltering, or when someone who is barefoot or is wearing open sandals stands on the scorpion. Animals are stung more often on the face, mouth or front feet.


Antivenom for the treatment of Southern African scorpion stings is manufactured by the South African Vaccine Producers (SAVP) at the National Health Laboratories in Johannesburg, South Africa.
The same dose of antivenom is used for children and adults. Scorpion antivenom is ineffective at treating a patient who has venom in the eyes. Allergic reactions to scorpion antivenom are uncommon or usually mild.

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